[Description of UTI in patients with renal transplantation admitted in labafinegad hospital from 1384 to 1385]

Background: the renal transplantation is now the treatment of choice for ESRD. Urinary tract is the most common site for infection after kidney transplantation. The different clinical and microbiological aspects of UTI in renal transplantation

Materials and Methods: in this cross-sectional study, the clinical manifestation at the time of admission, past medical history, the time of transplantation and the result of laboratory data including U/A, U/C and CBC of patients with kidney transplantation and probable UTI were collected and analysed in SPSS 11/5

Results: in 122 patients with UTI, 61 patients [50%] were admitted with fever, chilliness and weakness without urinary signs and symptoms. the interval between transplantation and infection was 1 month in 19 patients [15/6%], 1-3 month in 23 patients [18/9%], 3-6 month in 19 patients [15/6%] and 6-12 month in 12-patients [9/8%]. 49 patients were infected after 12 month. In 56 patients [45/9%] urine culture was negative and in the positive results, E coli was the most common [56%] organism

Conclusion: in this study UTI was occured most of the time in the first years after transplantation and was manifested with nonspecific signs and symptoms in most patients. Urine culture can be negative in near half of the cases

[Hemophagocytic lymphohistiocytosis and cases Report of secondry form]

Background: this Syndrom is rare, but aggressive and potentially life-threatening disease most often affects infants from birth to 18 months of age, but cases in older children and adults have been reported

Materials and Methods: cases Report Study in Masih daneshvary Hospital.All related records in this regard were collected from late year

Result: superiority of sexual[Men] and low mortality rate

Conclusions: because HLH is often fatal, one must have a high index of suspicion that patients who present with several of the following: high fevers, maculopapular rash, failure to thrive, central nervous system symptoms, hepatosplenomegaly, lymphadenopathy, cytopenias, coagulopathy, abnormal liver function tests, and high serum ferritin, Sudden decrease of ESR, may have HLH

Spectrophotometric method for the determination of metoclopramide

A simple and rapid spectrophotometric assay for the determination of metoclopramide hydrochloride in pure and dosage forms has been developed. It is based on the reaction between metoclopramide and 3-methyl-2-benzothiazolone hydrazone in the presence of ferric chloride to give a coloured product with a maximum absorbance at 556 nm. The results obtained are reproducible with a coefficient of variation less than 2% and in a good agreement with the official method. The proposed method is also applicable to urine samples

Application of derivative spectrophotometry to the determination of each of metoclopramide HCL and lignocaine HCL in pharmaceutical preparations

Derivative spectrophotometric methods were described for the determination of metoclopramide HCl and lignocaine HCl in dosage forms. The first drug was determined in suppositories, syrups, ampoules, tablets and drops. The second was determined in vials, jelly and ointments. The methods were efficient to correct for the interference due to additives viz. parabens and coadministered drugs as paracetamol and naphazoline. Results obtained were accurate with coefficient of variation less than 2%